Searchable abstracts of presentations at key conferences in endocrinology

ea0019p286 | Reproduction | SFEBES2009

Inhibin B and AMH are NOT predictors of serum testosterone in young men after cancer

Greenfield DM , Walters SJ , Ross RJM , Coleman RE , Hancock BW , Snowden JA , Ledger WL

Background: In men inhibin B is correlated with sperm count, concentration and testicular volume. Anti-müllerian hormone (AMH) is significantly positively correlated with inhibin B and significantly negatively correlated with FSH. Raised FSH is a traditional marker of infertility. Young male cancer patients treated with gonadotoxic agents are at high risk of hypogonadism (HG). The relationship between inhibin B and AMH with serum total testosterone is unclear.<p class...

ea0011p246 | Cytokines and growth factors | ECE2006

GH and GH antagonist B2036 effect on the immune system

Maamra M , Perna F , Colao A , Pivonello R , Zappacosta S , Ross RJM , Matarese G

Introduction: Growth Hormone (GH) receptors are expressed on, and GH is secreted by, human peripheral blood mononuclear cells (PBMCs). However, the role of GH in immunity has remained elusive and studies have given conflicting results. Experimental data strongly implicates a role for pituitary GH in the immune response of rodents. The data from knockout mice suggests that GH acts not as an obligate immunoregulator but as an anabolic and stress-modulating hormone. Despite the c...